{"id":3464,"date":"2022-05-09T14:17:00","date_gmt":"2022-05-09T07:17:00","guid":{"rendered":"https:\/\/prc.org.vn\/?p=3464"},"modified":"2022-07-27T07:41:50","modified_gmt":"2022-07-27T00:41:50","slug":"su-chuyen-doi-phuong-thuc-song-trong-chi-fusarium-dien-ra-thuong-xuyen-va-thieu-cac-chi-dau-ro-rang-trong-gen-cua-chung","status":"publish","type":"post","link":"https:\/\/prc.org.vn\/?p=3464","title":{"rendered":"S\u1ef1 chuy\u1ec3n \u0111\u1ed5i ph\u01b0\u01a1ng th\u1ee9c s\u1ed1ng trong chi fusarium di\u1ec5n ra th\u01b0\u1eddng xuy\u00ean v\u00e0 thi\u1ebfu c\u00e1c ch\u1ec9 d\u1ea5u r\u00f5 r\u00e0ng trong gen c\u1ee7a ch\u00fang"},"content":{"rendered":"\n

Chi n\u1ea5m Fusarium (Ascomycota) l\u00e0 m\u1ea7m m\u1ed1ng c\u1ee7a nhi\u1ec1u lo\u1ea1i b\u1ec7nh nghi\u00eam tr\u1ecdng \u0111\u1ed1i v\u1edbi th\u1ef1c v\u1eadt tr\u00ean to\u00e0n th\u1ebf gi\u1edbi, v\u00e0 nhi\u1ec1u lo\u00e0i trong s\u1ed1 \u0111\u00f3 \u0111\u00e3 \u0111\u01b0\u1ee3c gi\u1ea3i tr\u00ecnh t\u1ef1 b\u1ed9 gen. Chi n\u00e0y c\u00f3  c\u00e1c ph\u01b0\u01a1ng th\u1ee9c sinh s\u1ed1ng r\u1ea5t \u0111a d\u1ea1ng, ch\u00fang c\u0169ng \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y s\u1ed1ng k\u00fd sinh trong th\u1ef1c v\u1eadt r\u1ea5t ph\u1ed5 bi\u1ebfn (endophytes). Trong nghi\u00ean c\u1ee9u n\u00e0y, ch\u00fang t\u00f4i \u0111\u00e3 \u0111\u01b0a nh\u1eefng b\u1ed9 gen \u0111\u01b0\u1ee3c \u0111\u00e1nh d\u1ea5u v\u00e0o trong c\u1ea5u tr\u00fac c\u1ee7a 5 ch\u1ee7ng Fusarium<\/em> n\u1ed9i sinh, bao g\u1ed3m to\u00e0n b\u1ed9 b\u1ed9 gen \u0111\u1ea7u ti\u00ean c\u1ee7a ch\u1ee7ng n\u1ea5m Fusarium<\/em> chu\u1ed1i. S\u1ef1 t\u00e1i t\u1ed5 h\u1ee3p li\u00ean t\u1ee5c trong b\u1ed9 gen c\u1ee7a c\u00e1c ch\u1ee7ng Fusarium<\/em> c\u00f3 li\u00ean quan ch\u1eb7t ch\u1ebd v\u1edbi s\u1ef1 t\u1ea1i t\u1ea1o v\u00e0 bi\u1ebfn \u0111\u1ed5i l\u1ed1i s\u1ed1ng c\u1ee7a chi n\u1ea5m n\u00e0y, ch\u00fang t\u00f4i ch\u1ec9 t\u00ecm th\u1ea5y c\u00f3 duy nh\u1ea5t m\u1ed9t l\u1ea7n ch\u00fang c\u1ed9ng sinh v\u1edbi m\u1ed9t nh\u00f3m ngo\u1ea1i lai \u0111\u00f3 l\u00e0 c\u1ed9ng sinh v\u1edbi m\u1ed9t nh\u00f3m gen c\u00f4n tr\u00f9ng \u0111\u01a1n b\u00e0o. S\u1ef1 b\u1ea3o th\u1ee7 trong vi\u1ec7c t\u00e1i t\u1ed5 h\u1ee3p v\u1edbi c\u00e1c codon kh\u00e1c bi\u1ec7t v\u00e0 s\u1ef1 t\u1ed1i \u01b0u h\u00f3a trong t\u00e1i t\u1ed5 h\u1ee3p ch\u00ednh x\u00e1c c\u00e1c codon \u0111\u00e3 t\u00e1ch kh\u1ecfi c\u00e1c Fusarium sensu stricto trong c\u00f9ng m\u1ed9t chi. Ch\u00fang t\u00f4i c\u0169ng \u0111\u00e3 th\u1ef1c hi\u1ec7n vi\u1ec7c t\u00ednh to\u00e1n \u0111\u1ec3 d\u1ef1 \u0111o\u00e1n v\u1ec1 s\u1ef1 t\u00e1i t\u1ed5 h\u1ee3p \u0111\u1ec3 t\u1ea1o ra c\u00e1c protein t\u00e1i t\u1ed5 h\u1ee3p (CSEP) v\u00e0 c\u00e1c enzym ho\u1ea1t \u0111\u1ed9ng v\u1edbi carbohydrate (CAZymes) \u2014 c\u1ea3 hai emzyme \u0111\u1ec1u tham gia v\u00e0o qu\u00e1 tr\u00ecnh t\u01b0\u01a1ng t\u00e1c gi\u1eefa n\u1ea5m v\u00e0 v\u1eadt ch\u1ee7 \u2014 v\u00e0 v\u1edbi m\u1ee5c ti\u00eau \u0111\u1ec3 t\u00ecm ki\u1ebfm b\u1eb1ng ch\u1ee9ng trong t\u1ea7n xu\u1ea5t xu\u1ea5t hi\u1ec7n qua \u0111\u00f3 c\u00f3 th\u1ec3 d\u1ef1 \u0111o\u00e1n l\u1ed1i s\u1ed1ng ch\u00fang. Tuy nhi\u00ean, th\u00f4ng qua quan s\u00e1t c\u00e2y ph\u00e1t sinh c\u1ee7a c\u00e1c lo\u00e0i \u0111\u00e3 m\u00f4 t\u1ea3 th\u1ea5y s\u1ef1 bi\u1ebfn \u0111\u1ed5i c\u1ee7a gen th\u01b0\u1eddng xuy\u00ean h\u01a1n so v\u1edbi thay \u0111\u1ed5i ph\u01b0\u01a1ng th\u1ee9c s\u1ed1ng c\u1ee7a lo\u00e0i. Kh\u00f4ng c\u00f3 s\u1ef1 kh\u00e1c bi\u1ec7t \u0111\u00e1ng k\u1ec3 n\u00e0o trong CSEP v\u00e0 CAZyme, hay gen c\u1ee7a c\u00e1c ch\u1ee7ng n\u1ea5m g\u00e2y b\u1ec7nh c\u0169ng nh\u01b0 gen n\u1ed9i sinh, m\u1eb7c d\u00f9 ch\u00fang t\u00f4i \u0111\u00e3 t\u00ecm th\u1ea5y m\u1ed9t s\u1ed1 b\u1eb1ng ch\u1ee9ng c\u00f3 s\u1ef1 bi\u1ebfn \u0111\u1ed5i trong s\u1ed1 l\u01b0\u1ee3ng c\u00e1c gen \u0111\u01b0\u1ee3c nh\u00e2n b\u1ea3n c\u00f3 th\u1ec3 l\u00e0m ra t\u0103ng b\u1ec7nh. M\u1ed9t s\u1ed1 l\u01b0\u1ee3ng l\u1edbn c\u00e1c protein CSEP ph\u1ee5 (ngh\u0129a l\u00e0 \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y nhi\u1ec1u h\u01a1n 1 \u0111\u01a1n v\u1ecb ph\u00e2n lo\u1ea1i nh\u01b0ng kh\u00f4ng ph\u1ea3i t\u1ea5t c\u1ea3) v\u00e0 m\u1ed9t s\u1ed1 l\u01b0\u1ee3ng t\u01b0\u01a1ng \u0111\u1ed1i th\u1ea5p c\u00e1c ch\u1ee7ng protein CSEP ri\u00eang bi\u1ec7t \u0111i\u1ec1u \u0111\u00f3 cho th\u1ea5y c\u00f3 s\u1ef1 chuy\u00ean bi\u1ec7t \u0111\u1ed1i v\u1edbi c\u00e2y tr\u1ed3ng c\u1ee7a c\u00e1c lo\u00e0i Fusarium<\/em>. Ch\u00fang t\u00f4i c\u0169ng t\u00ecm th\u1ea5y m\u1ed9t n\u1eeda s\u1ed1 c\u00e1c gen l\u00f2ng c\u1ed1t \u0111\u01b0\u1ee3c ch\u1ecdn l\u1ecdc chuy\u00ean bi\u1ec7t v\u00e0 \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh c\u00e1c protein CSEP v\u00e0 enzym CAZyme c\u1ee5 th\u1ec3 \u0111\u1ec3 d\u1ef1 \u0111o\u00e1n c\u00f3 bi\u1ec3u hi\u1ec7n ch\u1ecdn l\u1ecdc tr\u00ean m\u1ed9t s\u1ed1 d\u00f2ng nh\u1ea5t \u0111\u1ecbnh. K\u1ebft qu\u1ea3 c\u1ee7a ch\u00fang t\u00f4i cho th\u1ea5y n\u1ea5m fusarium l\u00e0 sinh v\u1eadt b\u1eadc cao v\u00e0 ghi nh\u1eadn l\u00e0 g\u00e2y kh\u00f3 kh\u0103n trong vi\u1ec7c d\u1ef1 \u0111o\u00e1n kh\u1ea3 n\u0103ng g\u00e2y b\u1ec7nh trong nh\u00f3m.<\/p>\n\n\n\n

Xem b\u1ea3n \u0111\u1ea7y \u0111\u1ee7: t\u1ea1i \u0111\u00e2y<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Chi n\u1ea5m Fusarium (Ascomycota) l\u00e0 m\u1ea7m m\u1ed1ng c\u1ee7a nhi\u1ec1u lo\u1ea1i b\u1ec7nh nghi\u00eam tr\u1ecdng \u0111\u1ed1i v\u1edbi th\u1ef1c v\u1eadt tr\u00ean to\u00e0n th\u1ebf<\/p>\n","protected":false},"author":4,"featured_media":3468,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[39],"tags":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/prc.org.vn\/index.php?rest_route=\/wp\/v2\/posts\/3464"}],"collection":[{"href":"https:\/\/prc.org.vn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/prc.org.vn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/prc.org.vn\/index.php?rest_route=\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/prc.org.vn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3464"}],"version-history":[{"count":2,"href":"https:\/\/prc.org.vn\/index.php?rest_route=\/wp\/v2\/posts\/3464\/revisions"}],"predecessor-version":[{"id":3557,"href":"https:\/\/prc.org.vn\/index.php?rest_route=\/wp\/v2\/posts\/3464\/revisions\/3557"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/prc.org.vn\/index.php?rest_route=\/wp\/v2\/media\/3468"}],"wp:attachment":[{"href":"https:\/\/prc.org.vn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3464"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/prc.org.vn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=3464"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/prc.org.vn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=3464"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}